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Drosophila hybrid sterility : ウィキペディア英語版 | Drosophila hybrid sterility
The concept of a biological species as a group of organisms capable of interbreeding to produce viable offspring dates back to at least the 18th century, although it is often associated today with Ernst Mayr. Species of the fruit-fly Drosophila are one of the most commonly used organisms in evolutionary research, and have been used to test many theories related to the evolution of species. The genus Drosophila comprises numerous species that have varying degrees of premating and postmating isolation (including hybrid sterility) between them. These species are useful for testing hypotheses of the reproductive mechanisms underlying speciation. == Historical background ==
Working in the early 20th century T.H. Morgan, was the first to use Drosophila to explore heredity. Primarily on the basis of work with ''D. melanogaster'', Morgan and his colleagues C.B. Bridges, A.H. Sturtevant, and H.J. Mueller developed a chromosome theory of heredity, for which Morgan was awarded a Nobel Prize in 1933. Their experiments consisted of cross-breeding Drosophila mutants and documenting offspring. Another highly regarded figure in Drosophila research was Theodosius Dobzhansky, who invented the use of genetic markers and used them to study hybrid sterility between ''Drosophila pseudoobscura'' and ''Drosophila persimilis'' (Futuyma 1997). This experimental method has been used for many years.
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